Resources for health professionals to help couples with unexplained infertility
Important things to know about the adapted guideline
- Australian researchers and clinicians have developed and adapted the 2023 International ESHRE Guideline for an Australian context.
- The Australian Evidence-based Guideline for Unexplained Infertility: Adapted from the ESHRE Evidence-based Guideline for Unexplained Infertility was led through as a national
and international collaboration, is approved by the NHMRC, and is endorsed by The Royal Australian & New Zealand College of Obstetricians & Gynaecologists (RANZCOG) and the Fertility Society of Australia & New Zealand (FSANZ). - It has new evidence-based recommendations so that couples can make informed
decisions and try to avoid expensive, often ineffective, or unverified treatments. - It consulted national and international researchers and clinicians, and was developed in partnership with international fertility societies as well as patients, including those from indigenous, and culturally and linguistically diverse (CALD) backgrounds.
Our AskFertility App
The AskFertility App is for those with fertility issues and who think they may have unexplained infertility, those who already have a diagnosis.
The AskFertilityApp is a trustworthy and comprehensive App developed by the leading experts worldwide and co-designed with individuals dealing with infertility.
AskFertility has a range of features, including:
- Evidence-based information on fertility and unexplained infertility
- A dashboard with a period and symptoms tracker tool to help women understand their body and indicate the fertile window
Important things about unexplained infertility
For most couples, a cause of infertility can be identified, and it includes male and female factors with sperm & tubal problems.
- Unexplained infertility is diagnosed when doctors can’t find a specific reason why a couple is having trouble getting pregnant, even after running the usual tests. About 30% of couples dealing with infertility fall into this category. It’s a diagnosis that can be frustrating because there isn’t a clear cause to address.
- Despite this, it’s important to know that treatment options are available.
- For couples with unexplained infertility, the recommended treatment is often to start with Intrauterine Insemination (IUI) combined with medication to help stimulate the ovaries to produce more eggs and boost the chances of conception.
- In some cases, In Vitro Fertilization (IVF) might be considered, especially if other treatments haven’t worked.
- Dealing with infertility can be very stressful, so it is crucial to ensure emotional support is available.
Information about unexplained infertility
Click on the icons to open a series of fact sheets which we hope will help you inform couples with unexplained infertility.
What is unexplained infertility
Fertility testing
What factors affect fertility
Treatment options
Emotional Wellbeing
Fertility Treatment Experiences Resource
The Healthtalk Australia Infertility & Fertility Treatment Experiences Resource presents the experiences of 25 women and gender-diverse people living in Australia who have generously shared their stories of infertility and fertility treatment. It also features some short ‘explainers’ about different aspects of infertility and fertility treatment and links to other credible sources of information and support.
Fertility Treatment Experiences online resource is based on qualitative research conducted by researchers at RMIT University with clinical research support from the Monash Centre for Research and Implementation (MCHRI) and Robinson Research Institute, as part of the NHMRC Centre for Research Excellence in Women’s Health in Reproductive Life (CRE-WHiRL).
Contact us
If you have questions or feedback about the resource, please contact us.